Lucia Simonicova, PhD

Assistant Research Scientist

Publications

  1. Conway, T.P., Simonicova, L., Moye-Rowley, W.S. (2024) Overlapping coactivator function is required for transcriptional activation by the Candida glabrata Pdr1 transcription factor. Genetics 228(1):iyae115.
  2. Vu, B.G., Simonicova, L., Moye-Rowley, W.S. (2023) Calcineurin is required for Candida glabrata Pdr1 transcriptional activation. mBio. 14(6):e0241623.
  3. Simonicova L., Moye-Rowley W.S. (2023) Characterizing Candida glabrata Pdr1, a Hyperactive Transcription Factor Involved in Azole Resistance. Methods Mol Biol. 2658:169-179.
  4. Ollinger T.L., Vu B., Murante D., Parker J.E., Simonicova L., Doorley L., Stamnes M.A., Kelly S.L., Rogers P.D., Moye-Rowley W.S., Krysan D.J. (2021) Loss-of-Function ROX1 Mutations Suppress the Fluconazole Susceptibility of upc2AΔ Mutation in Candida glabrata, Implicating Additional Positive Regulators of Ergosterol Biosynthesis. mSphere. 6(6):e0083021.
  5. Simonicova, L., and Moye-Rowley, W.S. (2020) Functional information from clinically-derived drug resistant forms of the Candida glabrata Pdr1 transcription factor. PLoS Genet. 16(8):e1009005.
  6. Whaley, S.G., Caudle, K.E., Simonicova, L., Zhang, Q., Moye-Rowley, W.S., and Rogers, P.D. (2018) Jjj1 Is a Negative Regulator of Pdr1-Mediated Fluconazole Resistance in Candida glabrata. mSphere 3(1): e00466-17.
  7. Khakhina, S., Simonicova, L., Moye-Rowley, W.S. (2018) Positive autoregulation and repression of transactivation are key regulatory features of the Candida glabrata Pdr1 transcription factor. Mol Microbiol. 107(6):747-764.
  8. Rendekova, J., Ward, T.A., Simonicova, L., Thomas, P.H., Nosek, J., Tomaska, L., Chovanec, M. (2016) Mgm101: A double-duty Rad52-like protein. Cell Cycle. 15(23):3169-3176.
  9. Simonicova, L., Dudeková, H., Ferenc, J., Procházková, K., Nebohacova, M., Dusinsky, R., Nosek, J., Tomaska, L. (2015) Saccharomyces cerevisiae as a model forthe study of extranuclear functions of mammalian telomerase. Curr Genet. 61(4):517-27.
  10. Visacka, K., Hofr, C., Willcox, S., Necasova, I., Pavlouskova, J., Sepsiova, R., Wimmerova, M., Simonicova, L., Nosek, J., Fajkus, J., Griffith, J.D., and Tomaska, L. (2012) Synergism of the two Myb domains of Tay1 protein results in high affinity binding to telomeres. J Biol Chem 287(38):32206-15.

 

Presentations

 

 

Honors and Awards

 

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lucia-simonicova@uiowa.edu
BS in Biology, Comenius University, Bratislava, Slovakia (2008)
MS in Genetics, Comenius University, Bratislava, Slovakia (2010)
PhD in Genetics, Comenius University, Bratislava, Slovakia (2015)
Postdoctoral Scholar, University of Iowa, Iowa City, Iowa, USA (2021)